P01.08: Contribution of fetal nasal bone measurement in midtrimester Down syndrome screening
نویسندگان
چکیده
منابع مشابه
Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome
Imbalance in the metabolites levels which can potentially be related to certain fetal chromosomal abnormalities can stimulate mother's immune response to produce autoantibodies directed against proteins. The aim of the study was to determine the concentration of 9000 autoantibodies in maternal plasma to detect fetal Down syndrome. Method. We performed 190 amniocenteses and found 10 patients wit...
متن کاملNuchal translucency measurement in first trimester Down syndrome screening.
(1) Approximately three in every four fetuses with Down syndrome have increased nuchal translucency (NT), which is a larger than normal build-up of fluid at the back of the neck. (2) The ultrasound measurement of NT between 11 and 14 weeks' gestation, in combination with the mother's age and the levels of placental biochemical markers in her blood, can be used to detect approximately 84% of fet...
متن کاملFetal nasal bone in screening for trisomies 21, 18 and 13 and Turner syndrome at 11-13 weeks of gestation.
OBJECTIVE To investigate the performance of first-trimester screening for aneuploidies by including assessment of the fetal nasal bone in the combined test of maternal age, fetal nuchal translucency (NT) thickness, fetal heart rate (FHR) and serum free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). METHODS Screening by the combined test was pe...
متن کاملAlphafetoprotein in midtrimester Down's syndrome
Serum alphafetoprotein was estimated in fetuses with and without Down's syndrome or with other chromosome abnormalities from the 17th to the 28th week of pregnancy. In normal fetuses, the AFP level declines steadily during this period. Before 20 weeks, there was no difference in the serum AFP levels of the three groups of fetuses. After 20 weeks, the serum AFP level in cases of Down's syndrome ...
متن کاملScreening for Down syndrome
In 1866 J Langdon Down made the observation of a subgroup of patients with particular facial features and mental handicap in the outpatient department of the London Hospital 1. In the late 1950’s, it was shown that an extra acrocentric chromosome was present in persons with Down syndrome, resulting in a diploid chromosome number of 47. It is now known that Down syndrome results when either the ...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2005
ISSN: 0960-7692
DOI: 10.1002/uog.2242